A cliché hunchbacked evil scientist's assistant aspires to become a scientist himself, much to the displeasure of the rest of the evil science community.

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Maniac (1934)

An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.

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Mesa of Lost Women (1953)

A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.

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Carnal Redemption (NaN)

Dr Dilf, Nurse Meow and Nurse Spanks are trying to create a cure to the anti-death gas which was accidentally unleashed in the last film. The good doctor and his half dressed nurses are against the clock as a killer is after them and is determined to hunt them down.

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Idiocracy (2006)

To test its top-secret Human Hibernation Project, the Pentagon picks the most average Americans it can find - an Army private and a prostitute - and sends them to the year 2505 after a series of freak events. But when they arrive, they find a civilization so dumbed-down that they're the smartest people around.

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Doctor Butcher M.D. (1980)

After Malukan immigrants engage in a string of corpse mutilations at various New York City hospitals, a doctor and a morgue assistant travel to the Maluku Islands to investigate.

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Ruby & Quentin (2003)

After hiding his loot and getting thrown in jail, brooding outlaw Ruby befriends Quentin, a dim-witted and garrulous giant. After Quentin botches a solo escape attempt, they make a break together. Unable to shake the clumsy Quentin, Ruby is forced to take him along as he pursues his former partners in crime to avenge the death of the woman he loved and get to the money.

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The Giant of Metropolis (1961)

Obro the muscleman goes to Atlantis and sinks a death-ray king who knows the secret of immortality.

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The Island of Dr. Moreau (1996)

A shipwrecked sailor stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.

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The Cabbage Soup (1981)

Two buddy farmers are visited by aliens who like their domestic cabbage soup.

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The Avengers (1998)

British Ministry agent John Steed, under direction from "Mother", investigates a diabolical plot by arch-villain Sir August de Wynter to rule the world with his weather control machine. Steed investigates the beautiful Doctor Mrs. Emma Peel, the only suspect, but simultaneously falls for her and joins forces with her to combat Sir August.

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The Jacket (2005)

A military veteran goes on a journey into the future, where he can foresee his death and is left with questions that could save his life and those he loves.

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Dr. Strangelove or: How I Learned to Stop Worrying and Love the Bomb (1964)

After the insane General Jack D. Ripper initiates a nuclear strike on the Soviet Union, a war room full of politicians, generals and a Russian diplomat all frantically try to stop the nuclear strike.

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Doctor X (1932)

A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.

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Dr. Cyclops (1940)

Four explorers are summoned to Peru by the brilliant physicist Dr Thorkel. They discover a rich source of radium and a half-mad Thorkel who shrinks them down to one-fifth their normal size when they threaten to stop his unorthodox experimentation.

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Mimic (1997)

A disease carried by common cockroaches is killing Manhattan children. In an effort to stop the epidemic an entomologist, Susan Tyler, creates a mutant breed of insect that secretes a fluid to kill the roaches. This mutant breed was engineered to die after one generation, but three years later Susan finds out that the species has survived and evolved into a large, gruesome monster that can mimic human form.

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Paprika (2006)

When a machine that allows therapists to enter their patient's dreams is stolen, all hell breaks loose. Only a young female therapist can stop it and recover it before damage is done: Paprika.

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The Fly (1986)

When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.

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Spy Kids 2: The Island of Lost Dreams (2002)

Exploring the further adventures of Carmen and Juni Cortez, who have now joined the family spy business as Level 2 OSS agents. Their new mission is to save the world from a mad scientist living on a volcanic island populated by an imaginative menagerie of creatures. On this bizarre island, none of the Cortez's gadgets work and they must rely on their wits--and each other--to survive and save the day.

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Twins (1988)

Julius and Vincent Benedict are the results of an experiment that would allow for the perfect child. Julius was planned and grows to athletic proportions. Vincent is an accident and is somewhat smaller in stature. Vincent is placed in an orphanage while Julius is taken to a south seas island and raised by philosophers. Vincent becomes the ultimate low life and is about to be killed by loan sharks.

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Mystery Men (1999)

When Champion City's hero Captain Amazing is kidnapped by the recently paroled supervillain Casanova Frankenstein, a trio of average, everyday superheroes -- Mr. Furious, the Shoveler and the Blue Raja -- assemble a new super team to save him.