A ten year old girl named Angela leads her six year old sister, Ellie, through various regimens of 'purification' in an attempt to rid themselves of their evil, which she believes to be the cause of their mother's mental illness. Precocious, to say the least, Angela has visions of Lucifer coming to take her and her sister away, and one of her remedies for this is for them to remain within a circle of their dolls and toys until they see a vision of the virgin Mary come to them. But such thinking can only lead to an ending befitting of her own mental state.

Habit (1997)
It's autumn in New York. Sam has broken up with his girlfriend and his father has recently died. World-weary and sloppy drunk, he finds temporary solace in the arms of Anna, a mysterious vampire who draws him away from his friends and into a web of addiction and madness.

Diminished Capacity (2008)
A Chicago journalist suffering from memory loss takes leaves from his job and returns to his rural hometown, where he bonds with his Alzheimer's impaired uncle Rollie and his old flame.

Close to Home (2005)
Smadar (Smadar Sayar) and Mirit (Naama Schendar), both 18 years old, are assigned to patrol the streets of Jerusalem together as part of their military service. Worlds apart in their personality their initial frosty relationship changes to friendship as they deal with their own emotional issues, the crushes and break-ups in their love lives, as well as the political realities.

Staying Together (1989)
After their father abruptly sells the beloved family-owned restaurant that has employed them for years, the charismatic McDermott boys - hot-tempered Brian (Quill), lovelorn Kit (Mulroney) and jokester Duncan (Astin) - find themselves at odds with their parents and each other.

Fall Time (1995)
Three young men decide to plan a mock kidnapping, but everything goes wrong because a real bank robbery was already planned by two other guys.

Communion (1989)
A novelist's wife and son see him changed by an apparent encounter with aliens in the mountains.

I Don't Know (1971)
A truly major work, I Don’t Know observes the relationship between a lesbian and a transgender person who prefers to be identified somewhere in between male and female, in an expression of personal ambiguity suggested by the film’s title. This nonfiction film – an unusual, partly staged work of semi-verité – is the first of Spheeris’s films to fully embrace what would become her characteristic documentary style: probing, intimate, uncompromising. Preserved by the Academy Film Archive in 2014.

The Scream (1983)
A woman just out of prison gets a job in a nursing home and tries, unsuccessfully, to put her life back together.

Brittle (1997)
The parents of five sisters have been married for forty years; the daughters have gathered in the family beach house to make a video for them. The encounter is marked by many confrontations as well as cheerful moments. Reminiscent of the sweet children's poems that mother recited are countered by Elsschot's Marriage: 'He thought: I'll kill her and set light to the house...' It also turns out that father had once disappeared for eighteen months, a 'secret' that the daughters have different ideas about. Brittle, an intimate film version of a play written and performed by the same actresses, is about rivalry in a family, the right to silence, but also about the need for solidarity. At the Netherlands Film Festival in 1997 the Golden Calf for Best Actress was awarded to the five actresses together.

Brace (2015)
On his first foray out onto London's thriving gay scene, newly single Adam meets Rocky, a handsome and mysterious drifter, with whom he shares an instant and undeniable chemistry. From the outset, Rocky is eager to reveal more of himself than Adam is ready for, and so the two maintain an uncomfortable pact of silence. As the pair grow closer, something has to give, and the truth about Rocky is explosively revealed. As the dust settles, the men are left to decide whether they can find acceptance in each other, by facing the truth about themselves.

Amreeka (2009)
Eager to provide a better future for her son, Fadi, divorcée Muna Farah leaves her Palestinian homeland and takes up residence in rural Illinois -- just in time to encounter the domestic repercussions of America's disastrous war in Iraq. Now, the duo must reinvent their lives with some help from Muna's sister, Raghda, and brother-in-law, Nabeel.

Brief Interviews with Hideous Men (2009)
After her boyfriend mysteriously leaves her with little explanation, a doctoral candidate in anthropology at a prestigious East Coast university is left looking for answers as to what went wrong.

Camping with Ada (2016)
Romanian Ada faces the summer working as a prostitute with her aunt at a Norwegian camping site. When she encounters Henriette, a Norwegian girl, it sets a spark in her dream of a better life. Ada tries to push away reality, but as night falls the two worlds starts colliding.

Cockfighter (1974)
A man who trains fighting cocks vows to remain silent until one of his birds wins a championship.

Methodic (2007)
Possessed by an ominous presence known as "The Dollman", a young boy murders his parents in cold blood. Sentenced to a life under a microscope at the state mental hospital, "The Dollman" simply bides his time, dwelling within the boy, waiting for the day when he will become powerful enough to completely take over his human host and escape!

The Premature Burial (1962)
An artist grows distant from his new wife as an irrational fear of premature burial consumes him.

A Very Serious Person (2006)
Jan, an itinerant male nurse from Denmark, takes a new job with Mrs. A, a terminally ill Manhattan woman raising her parentless thirteen-year-old grandson, Gil. Spending the summer by the shore, the emotionally reserved Jan finds himself oddly cast as a mentor to Gil in having to prepare the sensitive boy for life with his cousins in Florida after his grandmother's death.

Psychopathia Sexualis (2006)
Multi-narrative adaptation of Richard v. Krafft-Ebing's notorious medico-forensic study of sexual perversity.

Wonderful World (2009)
Ben Singer is a failed children's folk singer, a career proofreader, a less-than-extraordinary weekend dad, and perhaps the most negative man alive. Floundering in all aspects of his life, Ben's only comfort comes from regular chess games and friendly debates on game theory with his Senegalese roommate Ibou. When Ibou is suddenly struck ill, Ben's pessimistic worldview seems unequivocally confirmed. It takes an extended visit from Ibou's sister Khadi for Ben to realize that cynicism may be all a matter of perspective.

Some Folks Call It a Sling Blade (1994)
25 years after committing a double murder, Karl Childers is going to be released from an institution for the criminally insane. A local reporter comes to talk to him, and listens in horror about his life leading up to the crime. This is the short film that inspired the full-length "Sling Blade".