A lab accident gives a beagle named Shoeshine some serious superpowers -- a secret that the dog eventually shares with the young boy who becomes his owner and friend.
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Innerspace (1987)
Test pilot Tuck Pendleton volunteers to test a special vessel for a miniaturization experiment. Accidentally injected into a neurotic hypochondriac, Jack Putter, Tuck must convince Jack to find his ex-girlfriend, Lydia Maxwell, to help him extract Tuck and his ship and re-enlarge them before his oxygen runs out.
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As Good as It Gets (1997)
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Chemistry and Love (1948)
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Without Family (2000)
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