A doctor finds a jungle laboratory, complete with mad scientist and genetic engineering experiments

Tears of Kali (2004)
Helmed by writer-director Andreas Marschall - and a piece of fiction passing as fact - the direct-to-video horror indie Tears of Kali returns to the early eighties and plunges into a nightmarish scenario wrought when several EST-like groups establish themselves in India. One of the more extreme communes, the Taylor-Eriksson cult, carries its "quest for self-knowledge" to a malevolent end, with numerous group members trapped, tortured, murdered and mutilated. Tears of Kali tells their twisted and disturbing story. Mathieu Carriere, Peter Martell, Cora Chilcott, Vronie Kiefer, and Nuran Celik head the ensemble cast.

The Quiet Earth (1985)
After a top-secret experiment misfires, a scientist may be the only man left alive in the world.

The Fly (1986)
When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.

Spy Kids 2: The Island of Lost Dreams (2002)
Exploring the further adventures of Carmen and Juni Cortez, who have now joined the family spy business as Level 2 OSS agents. Their new mission is to save the world from a mad scientist living on a volcanic island populated by an imaginative menagerie of creatures. On this bizarre island, none of the Cortez's gadgets work and they must rely on their wits--and each other--to survive and save the day.

The Invisible Man (1933)
After experimenting on himself and becoming invisible, scientist Jack Griffin, now aggressive due to the drug's effects, seeks a way to reverse the experiment at any cost.
Hand in Glove (1976)
To carry on his important work the ego-maniacal scientist Dr Kelly must obtain another hand… a hand which begins to take on a life of its own.
Two-faced Killer: A Modern Thriller (1951)
An adaptation of "The Strange Case of Doctor Jekyll and Mr. Hyde", heavily influenced by the Universal horror movies of the 1940s.

The Box (2009)
Norma and Arthur Lewis, a suburban couple with a young child, receive a simple wooden box as a gift, which bears fatal and irrevocable consequences. A mysterious stranger delivers the message that the box promises to bestow upon its owner $1 million with the press of a button. However pressing this button will simultaneously cause the death of another human being somewhere in the world; someone they don't know. With just 24 hours to have the box in their possession, Norma and Arthur find themselves in the cross-hairs of a startling moral dilemma and must face the true nature of their humanity.

Bride of the Gorilla (1951)
The owner of a plantation in the jungle marries a beautiful woman. Shortly afterward, he is plagued by a strange voodoo curse which transforms him into a gorilla. But is his transformation real or is it all in his head?

Bloodlust! (1961)
Two couples are on a boating trip when they come across an uncharted island. The four investigate and find themselves in the clutches of Dr. Albert Balleau, whose hobby is hunting both animals and humans… The group tries to escape only to be thwarted by Dr. Balleau and his henchmen.

Lust (1979)
"Libidine" is quite peculiar erotic horror about a scientist, who performs some kind of experiment on his snake. His adolescent daughter Anna has an erotic relationship with the snake.

Maniac (1934)
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.

Mesa of Lost Women (1953)
A mad scientist, Dr. Aranya (Jackie Coogan), has created giant spiders in his Mexican lab in Zarpa Mesa to create a race of superwomen by injecting spiders with human pituitary growth hormones. Women develop miraculous regenerative powers, but men mutate into disfigured dwarves. Spiders grow to human size and intelligence.

Mimic (1997)
A disease carried by common cockroaches is killing Manhattan children. In an effort to stop the epidemic an entomologist, Susan Tyler, creates a mutant breed of insect that secretes a fluid to kill the roaches. This mutant breed was engineered to die after one generation, but three years later Susan finds out that the species has survived and evolved into a large, gruesome monster that can mimic human form.

Paprika (2006)
When a machine that allows therapists to enter their patient's dreams is stolen, all hell breaks loose. Only a young female therapist can stop it and recover it before damage is done: Paprika.

After Death (1990)
A woman goes back to the island where her parents were killed. They had been working on a cure for cancer and accidentally raised the dead by angering a voodoo priest. With the woman is a group of mercenaries and they meet up with some other researchers. They raise the dead again and all hell breaks loose

Alive (2003)
Tenshu is imprisoned and sentenced to death for murdering the men who raped his girlfriend. However, he manages to survive his execution and is presented with an option: face another execution attempt or subject himself to their bizarre and dangerous experiments.

Brain Dead (1990)
In a battle of man versus machine, Martin, a top neurosurgeon who's studying brain malfunctions that cause mental illness, delves deep into his own mind to save himself from a megalomaniacal corporation.

Idiocracy (2006)
To test its top-secret Human Hibernation Project, the Pentagon picks the most average Americans it can find - an Army private and a prostitute - and sends them to the year 2505 after a series of freak events. But when they arrive, they find a civilization so dumbed-down that they're the smartest people around.

The Amazing Spider-Man (2012)
Peter Parker is an outcast high schooler abandoned by his parents as a boy, leaving him to be raised by his Uncle Ben and Aunt May. Like most teenagers, Peter is trying to figure out who he is and how he got to be the person he is today. As Peter discovers a mysterious briefcase that belonged to his father, he begins a quest to understand his parents' disappearance – leading him directly to Oscorp and the lab of Dr. Curt Connors, his father's former partner. As Spider-Man is set on a collision course with Connors' alter ego, The Lizard, Peter will make life-altering choices to use his powers and shape his destiny to become a hero.