After the death of his wife, a grieving man becomes the victim of a horrific experiment to cure his addiction.
Needlestick (2017)
A desperate doctor locks down South Union Cardiac Hospital to keep the greatest discovery in human history to himself, while a young intern races to save a dying young dancer, his ex-girlfriend, and his best friend, and stop his mentor.
Darkman (1990)
Dr. Peyton Westlake is on the verge of realizing a major breakthrough in synthetic skin when his laboratory is destroyed by gangsters. Having been burned beyond recognition and forever altered by an experimental medical procedure, Westlake becomes known as Darkman, assuming alternate identities in his quest for revenge and a new life with a former love.
Innerspace (1987)
Test pilot Tuck Pendleton volunteers to test a special vessel for a miniaturization experiment. Accidentally injected into a neurotic hypochondriac, Jack Putter, Tuck must convince Jack to find his ex-girlfriend, Lydia Maxwell, to help him extract Tuck and his ship and re-enlarge them before his oxygen runs out.
Dark City (1998)
A man struggles with memories of his past, including a wife he cannot remember, in a nightmarish world with no sun and run by beings with telekinetic powers who seek the souls of humans.
Tears of Kali (2004)
Helmed by writer-director Andreas Marschall - and a piece of fiction passing as fact - the direct-to-video horror indie Tears of Kali returns to the early eighties and plunges into a nightmarish scenario wrought when several EST-like groups establish themselves in India. One of the more extreme communes, the Taylor-Eriksson cult, carries its "quest for self-knowledge" to a malevolent end, with numerous group members trapped, tortured, murdered and mutilated. Tears of Kali tells their twisted and disturbing story. Mathieu Carriere, Peter Martell, Cora Chilcott, Vronie Kiefer, and Nuran Celik head the ensemble cast.
The Quiet Earth (1985)
After a top-secret experiment misfires, a scientist may be the only man left alive in the world.
The Island of Dr. Moreau (1996)
A plane crash surviving attorney stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.
Hollow Man (2000)
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.
Logan (2017)
In the near future, a weary Logan cares for an ailing Professor X in a hideout on the Mexican border. But Logan's attempts to hide from the world and his legacy are upended when a young mutant arrives, pursued by dark forces.
Idiocracy (2006)
To test its top-secret Human Hibernation Project, the Pentagon picks the most average Americans it can find - an Army private and a prostitute - and sends them to the year 2505 after a series of freak events. But when they arrive, they find a civilization so dumbed-down that they're the smartest people around.
The Wave (2008)
A school teacher discusses types of government with his class. His students find it too boring to repeatedly go over national socialism and believe that dictatorship cannot be established in modern Germany. He starts an experiment to show how easily the masses can become manipulated.
Beyond Re-Animator (2003)
Once again tampering with mother nature to disastrous results, Dr. Herbert West continues his research while serving time in a maximum security prison for his previous exploits. West's limited prison-cell experiments are suddenly interrupted by the arrival of a new prison doctor and the brother of the girl who suffered from West's experiments 13 years earlier.
Black Friday (1940)
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.
From Beyond (1986)
The Resonator, a powerful machine that can control the sixth sense, has killed its creator and sent his associate into an insane asylum. When a beautiful psychiatrist becomes determined to continue the experiment, she unwittingly opens the door to a hostile parallel universe.
Igor (2008)
A cliché hunchbacked evil scientist's assistant aspires to become a scientist himself, much to the displeasure of the rest of the evil science community.
Leviathan (1989)
Underwater deep-sea miners encounter a Soviet wreck and bring back a dangerous cargo to their base on the ocean floor with horrifying results. The crew of the mining base must fight to survive against a genetic mutation that hunts them down one by one.
The Fly (1958)
Industrialist François Delambre is called late at night by his sister-in-law, Helene Delambre, who tells him that she has just killed her husband, André. Reluctant at first, she eventually explains to the police that André invented a matter transportation apparatus and, while experimenting on himself, a fly entered the chamber during the matter transference.
The Rage (2007)
A crazed scientist experimenting with a rage virus on innocent victims in a laboratory in the woods. When his monstrous subjects escape and vultures devour their remains, they became mutations seeking to feed on humans.
Altered States (1980)
A research scientist explores the boundaries and frontiers of consciousness. Using sensory deprivation and hallucinogenic mixtures from native American shamans, he explores these altered states of consciousness and finds that memory, time, and perhaps reality itself are states of mind.
The Haunting (1963)
Dr. John Markway invites three distinct individuals to the eerie and isolated Hill House to be subjects for a sleep disorder study. The unfortunate guests discover that Markway is far more interested in the sinister mansion itself — and they soon see the true nature of its horror.