Happy couple Geoffrey and Lillian move out to a rural country location so Geoffrey can concentrate on his work. Shutting himself off in a shed out back, Geoffrey is slowly consumed by his work as well as his impending madness.
Silent Rage (1982)
A mentally ill man in a small Texas town goes on a killing rampage and is fatally wounded by police. When doctors use an experimental serum to bring him back to life, the killer develops superhuman strength and the town sheriff must pursue him.
Men Behind the Sun (1988)
The film is a graphic depiction of the war atrocities committed by the Japanese at Unit 731, the secret biological weapons experimentation unit of the Imperial Japanese Army during World War II. The film details the various cruel medical experiments Unit 731 inflicted upon the Chinese and Soviet prisoners at the tail-end of the war.
Hybrid (1997)
A group of space renegades hook up with a drifter named McQueen. Together they hole up in an abandoned research facility for the night and are relentlessly pursued by a human/monster hybrid.
Dread (2009)
Three college students set out to document what other people dread the most. However, one of the three turns out to secretly be a sadistic psychopath who uses this knowledge to gruesomely torture the subjects.
The Invisible Maniac (1990)
An invisible scientist escapes from an asylum and teaches high-school physics to nubile teens.
Island of Terror (1966)
A small island community is overrun with creeping, blobbish, tentacled monsters which liquefy and digest the bones from living creatures. The community struggles to fight back.
The Neanderthal Man (1953)
A scientist develops a formula which will cause animals to regress to the form of their primitive ancestors, and tries it on himself with disastrous results.
Before I Hang (1940)
Dr. John Garth conducting an innovative medical experiment aimed at prolonging life and combating aging. The experiment takes an unexpected turn, placing the doctor in a confrontation with the ethics of his work and the consequences of his research.
The Man They Could Not Hang (1939)
Dr. Henryk Savaard is a scientist working on experiments to restore life to the dead. When he is unjustly hanged for murder, he is brought back to life by his trusted assistant. Re-animated he turns decidedly nasty and sets about murdering the jury that convicted him.
The Island of Dr. Moreau (1977)
A ship-wrecked man floats ashore on an island in the Pacific Ocean. The island is inhabited by a scientist, Dr. Moreau, who in an experiment has turned beasts into human beings.
Raging Sharks (2005)
An oceanic observation station is in desperate trouble after a sudden shark attack wrecked the oxygen supply. The accompanying ship, a coast guard cruiser, and other ships in and around the Bermuda triangle are attacked as well. The US Navy sends a submarine to investigate, but soon they too are under attack.
Rejuvenatrix (1988)
A rich actress who has gotten too old for leading roles employs a scientist who is working on a formula for eternal youth. The formula involves withdrawing certain fluids from the human brain. She takes the serum, but its unforeseen side effects turn her into a murderous monster.
The Black Sleep (1956)
In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...
Face of Terror (1962)
A scientist develops a serum that can eradicate scar tissue. He tries it on a girl with a horribly disfigured face. It succeeds, but then he discovers the girl is an escaped mental patient from a local asylum.
Horror High (1973)
A nerdy high school super whiz experiments with a chemical which will transform his guinea pig "Mr. Mumps" from a gentle pet into a ravenous monster. In a fit of rage against his tormentors at the high school, Vernon Potts goes on a killing spree, eliminating all of those who ever picked on him - the Gym Coach, the School Jock, The Creepy Janitor & his hated teacher, Ms. Grindstaff.
Elves (1989)
While conducting a pagan ritual in the woods with her friends, Kirsten inadvertently awakens the spirit of a demonic Christmas elf involved in a neo-Nazi plot to bring about the master race. After the rent-a-Santa in her department store is murdered, an unemployed, alcoholic ex-cop takes the job and the two set out to unravel the mystery.
Project Vampire (1992)
A vampire scientist psychically charges the "longevity serum" he sells across the world, making all who use it into vampires loyal to him.
Bane (2008)
Held captive in an underground prison by a sadistic sicko who fancies himself a surgeon, 4 women fight for their lives, knowing the exact time they're scheduled to die thanks to a crudely carved set of numbers on each of their bodies. None of them can remember how they got there, but if any of them figure out the secret to their imprisonment, they stand at least some chance of surviving.
The Mutations (1974)
A mad scientist crosses plants with people, and the results wind up in a sideshow.
The Man Who Changed His Mind (1936)
Dr. Laurence, a once-respectable scientist, begins to research the origin of the mind and the soul. The science community rejects him, and he risks losing everything for which he has worked. He begins to use his discoveries to save his research and further his own causes, thereby becoming... a Mad Scientist, almost unstoppable...