In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...
Growth (2010)
In 1989, a breakthrough in "advanced parasitic research" on Cuttyhunk Island gave scientists a jump in human evolution. Initial tests proved promising, as subjects experienced heightened physical and mental strength and awareness. But - something in the experiment went horribly wrong, and the island mysteriously lost three quarters of its population.
In the Earth (2021)
As a deadly virus ravages the world, Dr. Martin Lowery embarks on a mission to reach test site ATU327A, a research hub deep in the Arboreal Forest. The arduous journey, guided by park scout Alma, is set back by a nighttime attack that leaves the two bruised and shoeless. When they run into Zach, a man living off the grid, they gratefully accept his help. Zach’s intentions aren’t exactly what they seem, however, and a path out of the forest and into safety quickly fades as the line between myth and science blurs.
Fake (1996)
Meet Dee Laytner and his half-Japanese partner, Ryo McLane, a pair of detectives from New York. Not only are these two always chasing down criminals, but Dee can't stop himself from trying to 'chase' Ryo. While on a trip to England, Dee hopes to make his feelings for Ryo known but uninvited guests and a string of murders gets in the way. The pair become involved in the local crime scene when Japanese Americans start turning up dead. Will Ryo be in danger?
Project Vampire (1992)
A vampire scientist psychically charges the "longevity serum" he sells across the world, making all who use it into vampires loyal to him.
Horror Hospital (1973)
Following his forced retirement from an appalling rock band, Jason decides to vacation at Brittlehouse Manor, a health farm run by the leather-gloved, ex-Nazi scientist Dr. Storm. Along the way, Jason meets Judy, also on her way to Brittlehouse Manor to visit her aunt, who married Dr. Storm some years ago. Once they arrive, the pair realise rather quickly that something is wrong, probably because the other guests have had their brains surgically removed, or all the blood pouring from the sink, or possibly just because the creepy midget keeps telling them to brush their teeth.
House of Dracula (1945)
A scientist working on cures for rare afflictions, such as a bone softening agent made from molds to allow him to correct the spinal deformity of his nurse, finds the physical causes of lycanthropy in wolf-man Larry Talbot and of vampirism in Count Dracula, but himself becomes afflicted with homicidal madness while exchanging blood with Dracula.
Bane (2008)
Held captive in an underground prison by a sadistic sicko who fancies himself a surgeon, 4 women fight for their lives, knowing the exact time they're scheduled to die thanks to a crudely carved set of numbers on each of their bodies. None of them can remember how they got there, but if any of them figure out the secret to their imprisonment, they stand at least some chance of surviving.
The Mutations (1974)
A mad scientist (Donald Pleasence) crosses plants with people, and the results wind up in a sideshow.
Tear Me Apart (2016)
In the wastelands of post-apocalyptic England, two young brothers turn to cannibalism to survive, only to fall for their prey, a teenage girl... and possibly the last female left alive.
The Fly (1986)
When Seth Brundle makes a huge scientific and technological breakthrough in teleportation, he decides to test it on himself. Unbeknownst to him, a common housefly manages to get inside the device and the two become one.
Spy Kids 2: The Island of Lost Dreams (2002)
Exploring the further adventures of Carmen and Juni Cortez, who have now joined the family spy business as Level 2 OSS agents. Their new mission is to save the world from a mad scientist living on a volcanic island populated by an imaginative menagerie of creatures. On this bizarre island, none of the Cortez's gadgets work and they must rely on their wits--and each other--to survive and save the day.
Brain Fix (1993)
Black-listed Professor Fued believes he has found a cure for acute schizophrenia by implanting living parasites into his patients' brains. When son Jeff witnesses his father at work he is appalled. He and apparently-normal patient Molly, whom he loves, are next on the treatment schedule...
Fantasctasy (2022)
Opening a collection of university horror shorts. A disturbed artist arrives home drugged after a party, without knowing it, the dark environment hides evil forces and now it is up to her to discern what is reality and what is not.
The Attic Expeditions (2001)
Trevor Blackburn is accused of murdering his girlfriend, Faith, in a brutal ritual. He's sentenced to live in an experimental rehabilitation community and falls into a coma. When he wakes up, he meets the mysterious Dr. Ek, who tortures Trevor in an attempt to learn the whereabouts of a powerful occult book. As other patients start to disappear, Trevor begins to wonder who and where he really is.
Doctor X (1932)
A wisecracking New York reporter intrudes on a research scientist's quest to unmask The Moon Killer.
Death Line (1972)
There's something pretty grisly going on under London in the Tube tunnels between Holborn and Russell Square. When a top civil servant becomes the latest to disappear down there Scotland Yard start to take the matter seriously. Helping them are a young couple who get nearer to the horrors underground than they would wish.
Dr. Cyclops (1940)
Four explorers are summoned to Peru by the brilliant physicist Dr Thorkel. They discover a rich source of radium and a half-mad Thorkel who shrinks them down to one-fifth their normal size when they threaten to stop his unorthodox experimentation.
Realive (2016)
Marc, a successful, ambitious man, is diagnosed with terminal cancer, and is given a few months to live. Unable to accept death, he decides to cryogenically freeze himself. The love of his life is devastated. Seventy years later, Marc becomes the first cryogenic resuscitated person in history. But this doesn't happen in the idealized way he dreamt of.