In 19th century England, a noted brain surgeon rescues a former student from being hanged on a false conviction for murder, and spirits him away to an ancient, repurposed abbey far in the countryside. There, he connives his pupil into assisting him in mapping the functions of the various parts of the human brain, using living subjects who are under a terrible animation-suspending drug called "black sleep". Subsequently, the student, along with the daughter of one of the subjects, discover that most of these subjects have survived but are being kept in a dungeon-like cellar, in various stages of physical and mental derangement...

Delirio (2009)
After a nuclear attack, a magician takes shelter in a forest with his assistant to complete his biggest magic trick to date, The Creation, a trick that requires that you do some of the most inhumane things known to man.

The Maker of Monsters (2018)
A depraved scientist falls madly in love with a young woman and turns her lover into a hideous monster for meddling in his diabolical plans.

Jacob's Ladder (1990)
After returning home from the Vietnam War, veteran Jacob Singer struggles to maintain his sanity. Plagued by hallucinations and flashbacks, Singer rapidly falls apart as the world and people around him morph and twist into disturbing images. His girlfriend, Jezzie, and ex-wife, Sarah, try to help, but to little avail. Even Singer's chiropractor friend, Louis, fails to reach him as he descends into madness.

The Fly (1958)
Industrialist François Delambre is called late at night by his sister-in-law, Helene, who tells him that she has just killed her husband. Reluctant at first, she eventually explains to the police that he invented a matter transportation apparatus and, while experimenting on himself, a fly entered the chamber.

The Philadelphia Experiment (1984)
Based on an "actual event" that took place in 1943. About a US Navy Destroyer Escort that disappeared from the Philadelphia Naval Shipyard, and sent two men 40 years into the future to 1984.

Athisayan (2007)
Devan is an orphan raised by Maya, an investigative journalist. When she is abducted before she can expose a high-profile group of criminals, Devan consumes an invisibility potion to try and save her.

Forever Young (1992)
A 1939 test pilot asks his best friend to use him as a guinea pig for a cryogenics experiment. Daniel McCormick wants to be frozen for a year so that he doesn't have to watch his love lying in a coma. The next thing Daniel knows is that he's been awoken in 1992.

The Fly II (1989)
Martin Brundle, born of the human/fly, is adopted by his father's place of employment (Bartok Inc.) while the employees simply wait for his mutant chromosomes to come out of their dormant state.

Alien³ (1992)
After escaping with Newt and Hicks from the alien planet, Ripley crash lands on Fiorina 161, a prison planet and host to a correctional facility. Unfortunately, although Newt and Hicks do not survive the crash, a more unwelcome visitor does. The prison does not allow weapons of any kind, and with aid being a long time away, the prisoners must simply survive in any way they can.

The Jacket (2005)
A military veteran goes on a journey into the future, where he can foresee his death and is left with questions that could save his life and those he loves.

Children of Men (2006)
In 2027, in a chaotic world in which humans can no longer procreate, a former activist agrees to help transport a miraculously pregnant woman to a sanctuary at sea, where her child's birth may help scientists save the future of humankind.

Darkman (1990)
Dr. Peyton Westlake is on the verge of realizing a major breakthrough in synthetic skin when his laboratory is destroyed by gangsters. Having been burned beyond recognition and forever altered by an experimental medical procedure, Westlake becomes known as Darkman, assuming alternate identities in his quest for revenge and a new life with a former love.

The Island of Dr. Moreau (1996)
A plane crash surviving attorney stumbles upon a mysterious island and is shocked to discover that a brilliant scientist and his lab assistant have found a way to combine human and animal DNA—with horrific results.

Hollow Man (2000)
Cocky researcher Sebastian Caine is working on a project to make living creatures invisible. Determined to achieve the ultimate breakthrough, Caine pushes his team to move to the next phase — using himself as the subject. The test is a success, but when the process can't be reversed and Caine seems doomed to future without flesh, he starts to turn increasingly dangerous.

Tears of Kali (2004)
Composed of three episodes—titled Kali, Shakti, and Devi—and linked within a narrative framework, it tells the story of the Taylor-Eriksson group, its members, and their extreme practices in search of awareness and liberation from karma. These practices, spiraling into violence and sex, ultimately turn into real nightmares.

The Quiet Earth (1985)
After a top-secret experiment misfires, a scientist may be the only man left alive in the world.

The Living and the Dead (2006)
Lord Donald and Lady Nancy reside in the magnificent but run-down Longleigh House with James, their mentally disabled adult son. Nancy has fallen seriously ill and Donald is preparing to sell the house to raise enough money to pay for an operation. He arranges for the family nurse, Mary, to take care of Nancy while he leaves to tend to the sale. However, James wants to prove to his father that he can look after his mother on his own and decides to lock Mary out of the house. It isn't long before James starts mixing his mother's pills and forgetting to take his own medication, and as the stress of looking after his mother increases, so too does the severity of his own condition.

Black Friday (1940)
University professor George Kingsley is struck by gangsters while crossing the street, leaving him with brain damage and one of the gangsters, Cannon, paralyzed. Kingsley's friend Dr. Sovac attends to both men, and when Cannon offers him a reward for aiding his recovery, Kovac transplants part of Cannon's brain into the dying Kingsley's skull, creating a dual personality.