A mad doctor uses patients at his isolated psychiatric institute as subjects in his attempts to create longevity by surgically installing an artificial gland in their skulls.
Emanuelle and the Last Cannibals (1977)
Intrepid photographer Emanuelle is taken deep into the Amazonian jungle to search for a cannibalistic tribe long believed to be extinct.
Voodoo Man (1944)
A mad doctor (Bela Lugosi) and his helpers (John Carradine, George Zucco) lure girls to his lab for brain work, to help his wife.
Unholy (2007)
Martha, a widow living in rural Pennsylvania, comes home to find her daughter about to blow her own head off with a shotgun in the basement of their house. Martha doesn't succeed in stopping her child's horrific demise, but the girl's death gradually leads the grieving mother to investigate a conspiracy that involves a legendary local witch, Nazi dabbling with the occult, and secret government experiments, with the story even referencing the fabled Philadelphia Experiment
Hellhole (1985)
An unlucky woman’s mother is murdered by a scarf-wielding killer named Silk, leaving the woman injured, traumatised and suffering from amnesia. She’s committed to a mental institution, where Silk follows her, looking for the papers he was trying to get from her mother. And Silk’s only the beginning of her problems, since the asylum is run by a mad doctor, performing experiments in chemical lobotomies!
The Man Who Could Cheat Death (1959)
Dr. Bonner plans to live forever through periodic gland transplants from younger, healthier human victims. Bonner looks about 40; he's really 104 years old. But people are starting to get suspicious, and he may not make 200.
The Mutations (1974)
A mad scientist crosses plants with people, and the results wind up in a sideshow.
Dracula (1931)
British estate agent Renfield travels to Transylvania to meet the mysterious Count Dracula, who is interested in leasing a castle in London. After Dracula enslaves Renfield and drives him to insanity, the pair sail to London together and Dracula, a secret vampire, begins preying on London socialites.
Shake, Rattle & Roll II (1990)
In "Multo", a young groom in Baguio for his honeymoon is possessed by a homicidal spirit when he discovers a cursed ring and decides to wear it. "Kulam" is set in the eerie halls of a mysterious hospital where a doctor practice voodoo and dead bodies go wandering in the night. "Aswang" is about a student who is a guest at a town fiesta in a remote province. The people's hospitable ways leave her clueless about a ritual that takes place at night.
The Abominable Dr. Phibes (1971)
After a team of surgeons botches his beloved wife's operation, the distraught Dr. Phibes unleashes a score of Old-Testament atrocities on his enemies.
Dr. Renault's Secret (1942)
A remake of the 1927 horror film "The Wizard". Dr. Larry Forbes arrives in a remote French village to visit his fiancée who lives with her scientist father Dr. Renault and his Ape-like manservant Noel. Several Murders coincide with Dr. Forbes arrival, with clues pointing in multiple directions.
Maniac (1934)
An ex-vaudeville actor is working as the assistant to a doctor who has Frankenstein aspirations. The ex-vaudeville actor kills the doctor and decides to assume the identity of the dead physician.
Don't Look in the Basement (1973)
A young psychiatric nurse goes to work at a lonesome asylum following a murder. There, she experiences varying degrees of torment from the patients.
Alraune (1952)
In the 1800s, a stormy love relationship develops quickly between a young medical student and a woman believing herself to be the daughter of his scientist uncle, the student having never heard of her before their chance encounter and both unaware that she is the result of the scientist's illegal experiments with artificial insemination..
Island of Lost Souls (1932)
An obsessed scientist conducts profane experiments in evolution, eventually establishing himself as the self-styled demigod to a race of mutated, half-human abominations.
Frankenstein (1931)
Tampering with life and death, Henry Frankenstein pieces together salvaged body parts to bring a human monster to life; the mad scientist's dreams are shattered by his creation's violent rage as the monster awakens to a world in which he is unwelcome.
The Erotic Rites of Frankenstein (1973)
Dr. Frankenstein is left for dead in the woods. His daughter, Dr. Vera Frankenstein, hunts for his attacker: Dr. Cagliostro, a mad scientist who’s created a race of human-animal hybrids.
I Was a Teenage Frankenstein (1957)
Professor Frankenstein creates a teenager from an accident victim, who gets angry when he learns he is going to be taken apart.
Frankenstein '80 (1972)
A mad scientist creates a monster called "Mosaico," who breaks out of the laboratory to hunt down and kill beautiful women.
Batman: The Doom That Came to Gotham (2023)
Explorer Bruce Wayne accidentally unleashes an ancient evil, and returns to Gotham after being away for two decades. There, Batman battles Lovecraftian supernatural forces and encounters allies and enemies such as Green Arrow, Ra's al Ghul, Mr. Freeze, Killer Croc, Two-Face and James Gordon.
Hellbound: Hellraiser II (1988)
Confined to a mental hospital, young Kirsty Cotton insists her supposedly dead father is stuck in hell, controlled by sadomasochistic demons after being betrayed by his evil, occult-obsessed wife, Julia. Few believe Kirsty, except the thrill-seeking Dr. Channard, who is intrigued by the young woman's lurid stories. So when Kirsty and fellow patient Tiffany head to hell for a rescue, Channard and Julia are close behind.